Shopping on line can be easy, simple and save you lots of money. It can also take a lot of your time, frustrate you, and result in unwanted purchases. Now the same can be said for regular high street shopping, but with the vast opportunity presented by the Internet it will pay you to spend a few minutes reading this and understanding how to better optimize your Pandemic shopping experience:

1. Compare - without doubt the biggest advantage that the Pandemic offers shoppers today is the ability to compare thousands of Pandemic at a time. This is a great thing, but not necessarily all the time! Too much can be daunting at times so take advantage of the great comparison sites and where possible let them do the hard work for you.

2. Research - if it has been said it will be on the internet. Ignorance is no longer a justifiable reason for buying the wrong thing. Take the time to research in detail everything that you could possible want to know about

3. Testimonials - don't know anybody that has bought a Pandemic? Wrong! If the Pandemic is good the internet will let you know. Use the Internet as a friend and get testimonials before you buy.

4. Questions - Got a question about Pandemic then search the Forums, FAQ's, Blogs etc. Don't be afraid to ask .....

5. Reputation - Never heard of the company selling Pandemic? Don't worry, no reason why you should know every company in the world, but you know someone that does! Use the internet to find out what people are saying about Pandemic and build up a picture of their reputation for sales, returns, customer service, delivery etc.

6. Returns - still worried that even after all of the above your Pandemic wont be what you want? Check out the returns policy. There is so much competition now that someone, somewhere is bound to offer the terms that you are comfortable with.

7. Feedback - happy with your Pandemic then let people know, after all you are depending on others people input in your buying decision, so why not give a little back.

8. Security - check for the yellow padlock on the Pandemic site before you buy, and the s after http:/ /i.e. https:// = a secure site

9. Contact - got a question about Pandemic, or want to leave a comment then check out the sites contact page. Reputable companies have them and respond.

10. Payment - ready to pay for your Pandemic, then use your credit card or PayPal! Be aware of companies that don't accept them, there may be genuine reasons but given the huge amount of choice you have when buying online there is no reason at all not to buy via credit card or PayPal.

A pandemic (from Greek language παν pan all + δήμος demos people) is an epidemic that spreads through human populations across a large region (for example a continent), or even worldwide.

Definition According to the World Health Organization (WHO), a pandemic can start when three conditions have been met:

• the emergence of a disease new to the population.
• the agent infects humans, causing serious illness.
• the agent spreads easily and sustainably among humans.

A disease or condition is not a pandemic merely because it is widespread or kills many people; it must also be infectious. For example cancer is responsible for many deaths but is not considered a pandemic because the disease is not infectious or contagious (although certain causes of some types of cancer might be).

WHO pandemic influenza phases The WHO global influenza preparedness plan defines the stages of pandemic influenza, outlines the role of WHO and makes recommendations for national measures before and during a pandemic. The phases are:

Interpandemic period:

• Phase 1: No new influenza virus subtypes have been detected in humans.
• Phase 2: No new influenza virus subtypes have been detected in humans, but an animal variant threatens human disease.

Pandemic alert period:

• Phase 3: Human infection(s) with a new subtype but no human-to-human spread.
• Phase 4: Small cluster(s) with limited localized human-to-human transmission
• Phase 5: Larger cluster(s) but human-to-human spread still localized.

Pandemic period:

• Phase 6: Pandemic: increased and sustained transmission in general population.

Pandemics and notable epidemics through history There have been a number of significant pandemics recorded in human history, generally zoonosis that came about with domestication of animals — such as influenza and tuberculosis. There have been a number of particularly significant epidemics that deserve mention above the "mere" destruction of cities:

• Peloponnesian War, 430 BC. Typhoid fever killed a quarter of the Athenian troops and a quarter of the population over four years. This disease fatally weakened the dominance of Athens, but the sheer virulence of the disease prevented its wider spread; i.e. it killed off its hosts at a rate faster than they could spread it. The exact cause of the plague was unknown for many years; in January 2006, researchers from the University of Athens analyzed teeth recovered from a mass grave underneath the city, and confirmed the presence of bacteria responsible for typhoid.

• Antonine Plague, 165–180. Possibly smallpox brought back from the Near East; killed a quarter of those infected and up to five million in all. At the height of a second outbreak (251–266) 5,000 people a day were said to be dying in Rome.

• Plague of Justinian, from 541 to 750, was the first recorded outbreak of the bubonic plague. It started in Egypt and reached Constantinople the following spring, killing (according to the Byzantine chronicler Procopius) 10,000 a day at its height and perhaps 40 percent of the city's inhabitants. It went on to eliminate a quarter to a half of the human population that it struck throughout the known world. Cambridge Catalogue page "Plague and the End of Antiquity" Quotes from book "Plague and the End of Antiquity" Lester K. Little, ed., Plague and the End of Antiquity: The Pandemic of 541-750, Cambridge, 2006. ISBN 0-521-84639-0
• The Black Death, started 1300s. Eight hundred years after the last outbreak, the bubonic plague returned to Europe. Starting in Asia, the disease reached Mediterranean and western Europe in 1348 (possibly from Italian merchants fleeing fighting in the Crimea), and killed twenty million Europeans in six years, a quarter of the total population and up to a half in the worst-affected urban areas. Plague - LoveToKnow 1911

• Cholera
• first pandemic 1816–1826. Previously restricted to the Indian subcontinent, the pandemic began in Bengal, then spread across India by 1820. It extended as far as China and the Caspian Sea before receding.
• The second pandemic (1829–1851) reached Europe, London in 1832, Ontario Canada and New York in the same year, and the Pacific coast of North America by 1834.
• The third pandemic (1852–1860) mainly affected Russia, with over a million deaths.
• The fourth pandemic (1863–1875) spread mostly in Europe and Africa.
• In 1866 there was an outbreak in North America.
• In 1892 cholera contaminated the water supply of Hamburg, Germany, and caused 8,606 deaths.John M. Barry, (2004). The Great Influenza: The Epic Story of the Greatest Plague in History. Viking Penguin. ISBN 0-670-89473-7.
• The seventh pandemic (1899–1923) had little effect in Europe because of advances in public health, but Russia was badly affected again.
• The eighth pandemic began in Indonesia in 1961, called El Tor after the strain, and reached Bangladesh in 1963, India in 1964, and the Soviet Union in 1966.

• Influenza
• The "first" pandemic of 1510 travelled from Africa and spread across Europe.Beveridge, W.I.B. (1977) Influenza: The Last Great Plague: An Unfinished Story of Discovery, New York: Prodist. ISBN 0-88202-118-4.
  • The "Asiatic Flu", 1889–1890. Was first reported in May of 1889 in Bukhara, Russia. By October, it had reached Tomsk and the Caucasus. It rapidly spread west and hit North America in December 1889, South America in February–April 1890, India in February-March 1890, and Australia in March–April 1890. It was purportedly caused by the H2N8 type of flu virus and had a very high attack and mortality rate.
  • The "Spanish flu", 1918–1919. First identified early March 1918 in US troops training at Fort Riley, Kansas, by October 1918 it had spread to become a world-wide pandemic on all continents. Unusually deadly and virulent, it ended nearly as quickly as it began, vanishing completely within 18 months. In six months, 25 million were dead; some estimates put the total of those killed worldwide at over twice that number. An estimated 17 million died in India, 500,000 in the United States and 200,000 in the UK. The virus was recently reconstructed by scientists at the Centers for Disease Control and Prevention studying remains preserved by the Alaskan permafrost. They identified it as a type of H1N1 virus.
  • The "Asian Flu", 1957–58. An H2N2 caused about 70,000 deaths in the United States. First identified in China in late February 1957, the Asian flu spread to the United States by June 1957.
  • The "Hong Kong Flu", 1968–69. An H3N2 caused about 34,000 deaths in the United States. This virus was first detected in Hong Kong in early 1968 and spread to the United States later that year. Influenza A (H3N2) viruses still circulate today.
  
  
  
  • Typhus, sometimes called "camp fever" because of its pattern of flaring up in times of strife. (It is also known as "gaol fever" and "ship fever", for its habits of spreading wildly in cramped quarters, such as jails and ships.) Emerging during the Crusades, it had its first impact in Europe in 1489 in Spain. During fighting between the Christian Spaniards and the Muslims in Granada, the Spanish lost 3,000 to war casualties and 20,000 to typhus. In 1528 the French lost 18,000 troops in Italy and lost supremacy in Italy to the Spanish. In 1542, 30,000 people died of typhus while fighting the Ottoman Empire in the Balkans. The disease also played a major role in the destruction of Napoleon's La Grande Armée in Russia in 1812. Typhus also killed numerous prisoners in the Nazi concentration camps during World War II.
  
  
  
  • Effects of Colonization. Encounters between European explorers and populations in the rest of the world often introduced local epidemics of extraordinary virulence. Disease killed the entire native (Guanches) population of the Canary Islands in the 16th century. Half the native population of Hispaniola in 1518 was killed by smallpox. Smallpox also ravaged Mexico in the 1520s, killing 150,000 in Tenochtitlán alone, including the emperor, and Peru in the 1530s, aiding the European conquerors. Measles killed a further two million Mexican natives in the 1600s. Some believe that the death of 90 to 95 percent of the Population history of American indigenous peoples of the New World was caused by Old World diseases. As late as 1848–49, as many as 40,000 out of 150,000 Hawaiians are estimated to have died of measles, whooping cough and influenza. The Story Of... Smallpox Smallpox: Eradicating the Scourge
  
  
  There are also a number of unknown diseases that were extremely serious but have now vanished, so the etiology of these diseases cannot be established. The cause of Sweating sickness in 16th-century England, which struck people down in an instant and was more greatly feared even than the bubonic plague, is still unknown.
  
  Concern about possible future pandemics Ebola virus and other quickly lethal diseases Lassa fever, Rift Valley fever, Marburg virus, Ebola and Bolivian hemorrhagic fever are highly contagious and deadly diseases with the theoretical potential to become pandemics. Their ability to spread efficiently enough to cause a pandemic is limited, however, as transmission of these viruses requires close contact with the infected vector. Furthermore, the short time between a vector becoming infectious and the onset of symptoms allows medical professionals to quickly quarantine vectors and prevent them from carrying the pathogen elsewhere. Genetic mutations could occur which could elevate their potential for causing widespread harm, thus close observation by contagious disease specialists is merited.
  
  Antibiotic resistance Antibiotic-resistant "superbugs" may also revive diseases previously regarded as "conquered." Cases of tuberculosis resistant to all traditionally effective treatments have emerged to the great concern of health professionals.
  
  Such common bacteria as Staphylococcus aureus, Serratia marcescens and species of Enterococcus that have developed resistance to the strongest available antibiotics such as vancomycin emerged in the past 20 years as an important cause of hospital-acquired nosocomial infections, and are now colonizing and causing disease in the general population.
  
  In the U.S., 2,000,000 people per year are catching hospital-acquired infections after having been admitted to hospitals to receive medical care for unrelated reasons. The latest number of infections are startling, (2006) equating to 4 new cases per minute. Of those, 90,000+ people die. Organizations like the Center for Disease Control, WHO and Safe Care Campaign are leading the effort to eradicate these avoidable, yet deadly infections.
  
  HIV infection HIV — the virus that causes AIDS — is now considered a global pandemic with infection rates as high as 25% in southern and eastern Africa. Effective education about safer sexual practices and bloodborne infection precautions training have helped to slow down infection rates in several African countries sponsoring national education programs. Infection rates are rising again in Asia and the Americas.
  
  SARS In 2003, there were concerns that Severe acute respiratory syndrome, a new, highly contagious form of atypical pneumonia caused by a coronavirus dubbed SARS-CoV, might become pandemic. Rapid action by national and international health authorities such as the World Health Organization helped slow transmission and eventually broke the chain of transmission, ending the localized epidemics before they could become a pandemic. The disease has not been eradicated, however, and could re-emerge unexpectedly, warranting monitoring and case reporting of suspicious cases of atypical pneumonia.
  
  Avian flu Wild aquatic birds are the natural hosts for a range of influenza A viruses. Occasionally viruses are transmitted from these species to other species and may then cause outbreaks in domestic poultry or (rarely) give rise to a human pandemic.
  
  In February 2004, avian influenza virus was detected in birds in Vietnam, increasing fears of the emergence of new variant strains. It is feared that if the avian influenza virus combines with a human influenza virus (in a bird or a human), the new subtype created could be both highly contagious and highly lethal in humans. Such a subtype could cause a global influenza pandemic, similar to the Spanish Flu, or the lower mortality pandemics such as the Asian Flu and the Hong Kong Flu.
  
  From October 2004 to February 2005, some 3,700 test kits of the 1957 Asian Flu virus were accidentally spread around the world from a lab in the US.
  
  In May 2005, scientists urgently call nations to prepare for a global influenza pandemic that could strike as much as 20% of the world's population.
  
  In October 2005, cases of the avian flu (the deadly strain H5N1) were identified in Turkey. EU Health Commissioner Markos Kyprianou said: "We have received now confirmation that the virus found in Turkey is an avian flu H5N1 virus. There is a direct relationship with viruses found in Russia, Mongolia and China." Cases of bird flu were also identified shortly thereafter in Romania, and then Greece. Possible cases of the virus have also been found in Croatia, Bulgaria and in the United Kingdom.. However, by the end of October only 67 people had died as a result of H5N1 which was atypical of previous influenza pandemics.
  
  Despite sensational media reporting, avian flu cannot yet be categorized as a "pandemic" because the virus cannot yet cause sustained and efficient human-to-human transmission. Cases so far are recognized to have been transmitted from bird to human, but as of December 2006 there have been very few (if any) cases of proven human-to-human transmission. Regular influenza viruses establish infection by attaching to receptors in the throat and lungs, but the avian influenza virus can only attach to receptors located deep in the lungs of humans, requiring close, prolonged contact with infected patients and thus limiting person-to-person transmission. The current WHO phase of pandemic alert is level 3, described as "no or very limited human-to-human transmission."
  
  See also
  • Centers for Disease Control and Prevention (CDC)
  • European Centre for Disease Prevention and Control (ECDC)
  • Endemic (epidemiology)
  • Epidemic
  • List of epidemics
  • Influenza pandemic
  • Pandemic Severity Index
  • Syndemic
  • Medieval demography
  • Infectious disease#Mortality from infectious diseases
  • Biological warfare
  • Disaster#Causes of hypothetical future disasters
  
  
  References
  • Steward's "The Next Global Threat: Pandemic Influenza".
  
  
  Further reading
  • WHO - Authoritative source of information about global health issues
  • Past pandemics that ravaged Europe
  • CDC: Influenza Pandemic Phases
  • U.S. government's pandemic flu and avian flu information site
  
  
  
  
  A pandemic (from Greek language παν pan all + δήμος demos people) is an epidemic that spreads through human populations across a large region (for example a continent), or even worldwide.
  
  Definition According to the World Health Organization (WHO), a pandemic can start when three conditions have been met:
  
  
  • the emergence of a disease new to the population.
  • the agent infects humans, causing serious illness.
  • the agent spreads easily and sustainably among humans.
  
  
  A disease or condition is not a pandemic merely because it is widespread or kills many people; it must also be infectious. For example cancer is responsible for many deaths but is not considered a pandemic because the disease is not infectious or contagious (although certain causes of some types of cancer might be).
  
  WHO pandemic influenza phases The WHO global influenza preparedness plan defines the stages of pandemic influenza, outlines the role of WHO and makes recommendations for national measures before and during a pandemic. The phases are:
  
  Interpandemic period:
  • Phase 1: No new influenza virus subtypes have been detected in humans.
  • Phase 2: No new influenza virus subtypes have been detected in humans, but an animal variant threatens human disease.
  Pandemic alert period:
  • Phase 3: Human infection(s) with a new subtype but no human-to-human spread.
  • Phase 4: Small cluster(s) with limited localized human-to-human transmission
  • Phase 5: Larger cluster(s) but human-to-human spread still localized.
  Pandemic period:
  • Phase 6: Pandemic: increased and sustained transmission in general population.
  
  
  Pandemics and notable epidemics through history There have been a number of significant pandemics recorded in human history, generally zoonosis that came about with domestication of animals — such as influenza and tuberculosis. There have been a number of particularly significant epidemics that deserve mention above the "mere" destruction of cities:
  
  
  • Peloponnesian War, 430 BC. Typhoid fever killed a quarter of the Athenian troops and a quarter of the population over four years. This disease fatally weakened the dominance of Athens, but the sheer virulence of the disease prevented its wider spread; i.e. it killed off its hosts at a rate faster than they could spread it. The exact cause of the plague was unknown for many years; in January 2006, researchers from the University of Athens analyzed teeth recovered from a mass grave underneath the city, and confirmed the presence of bacteria responsible for typhoid.
  
  
  
  • Antonine Plague, 165–180. Possibly smallpox brought back from the Near East; killed a quarter of those infected and up to five million in all. At the height of a second outbreak (251–266) 5,000 people a day were said to be dying in Rome.
  
  
  
  • Plague of Justinian, from 541 to 750, was the first recorded outbreak of the bubonic plague. It started in Egypt and reached Constantinople the following spring, killing (according to the Byzantine chronicler Procopius) 10,000 a day at its height and perhaps 40 percent of the city's inhabitants. It went on to eliminate a quarter to a half of the human population that it struck throughout the known world. Cambridge Catalogue page "Plague and the End of Antiquity" Quotes from book "Plague and the End of Antiquity" Lester K. Little, ed., Plague and the End of Antiquity: The Pandemic of 541-750, Cambridge, 2006. ISBN 0-521-84639-0
  • The Black Death, started 1300s. Eight hundred years after the last outbreak, the bubonic plague returned to Europe. Starting in Asia, the disease reached Mediterranean and western Europe in 1348 (possibly from Italian merchants fleeing fighting in the Crimea), and killed twenty million Europeans in six years, a quarter of the total population and up to a half in the worst-affected urban areas. Plague - LoveToKnow 1911
  
  
  
  • Cholera
  • first pandemic 1816–1826. Previously restricted to the Indian subcontinent, the pandemic began in Bengal, then spread across India by 1820. It extended as far as China and the Caspian Sea before receding.
  • The second pandemic (1829–1851) reached Europe, London in 1832, Ontario Canada and New York in the same year, and the Pacific coast of North America by 1834.
  • The third pandemic (1852–1860) mainly affected Russia, with over a million deaths.
  • The fourth pandemic (1863–1875) spread mostly in Europe and Africa.
  • In 1866 there was an outbreak in North America.
  • In 1892 cholera contaminated the water supply of Hamburg, Germany, and caused 8,606 deaths.John M. Barry, (2004). The Great Influenza: The Epic Story of the Greatest Plague in History. Viking Penguin. ISBN 0-670-89473-7.
  • The seventh pandemic (1899–1923) had little effect in Europe because of advances in public health, but Russia was badly affected again.
  • The eighth pandemic began in Indonesia in 1961, called El Tor after the strain, and reached Bangladesh in 1963, India in 1964, and the Soviet Union in 1966.
  
  
  
  • Influenza
  • The "first" pandemic of 1510 travelled from Africa and spread across Europe.Beveridge, W.I.B. (1977) Influenza: The Last Great Plague: An Unfinished Story of Discovery, New York: Prodist. ISBN 0-88202-118-4.
    • The "Asiatic Flu", 1889–1890. Was first reported in May of 1889 in Bukhara, Russia. By October, it had reached Tomsk and the Caucasus. It rapidly spread west and hit North America in December 1889, South America in February–April 1890, India in February-March 1890, and Australia in March–April 1890. It was purportedly caused by the H2N8 type of flu virus and had a very high attack and mortality rate.
    • The "Spanish flu", 1918–1919. First identified early March 1918 in US troops training at Fort Riley, Kansas, by October 1918 it had spread to become a world-wide pandemic on all continents. Unusually deadly and virulent, it ended nearly as quickly as it began, vanishing completely within 18 months. In six months, 25 million were dead; some estimates put the total of those killed worldwide at over twice that number. An estimated 17 million died in India, 500,000 in the United States and 200,000 in the UK. The virus was recently reconstructed by scientists at the Centers for Disease Control and Prevention studying remains preserved by the Alaskan permafrost. They identified it as a type of H1N1 virus.
    • The "Asian Flu", 1957–58. An H2N2 caused about 70,000 deaths in the United States. First identified in China in late February 1957, the Asian flu spread to the United States by June 1957.
    • The "Hong Kong Flu", 1968–69. An H3N2 caused about 34,000 deaths in the United States. This virus was first detected in Hong Kong in early 1968 and spread to the United States later that year. Influenza A (H3N2) viruses still circulate today.
    
    
    
    • Typhus, sometimes called "camp fever" because of its pattern of flaring up in times of strife. (It is also known as "gaol fever" and "ship fever", for its habits of spreading wildly in cramped quarters, such as jails and ships.) Emerging during the Crusades, it had its first impact in Europe in 1489 in Spain. During fighting between the Christian Spaniards and the Muslims in Granada, the Spanish lost 3,000 to war casualties and 20,000 to typhus. In 1528 the French lost 18,000 troops in Italy and lost supremacy in Italy to the Spanish. In 1542, 30,000 people died of typhus while fighting the Ottoman Empire in the Balkans. The disease also played a major role in the destruction of Napoleon's La Grande Armée in Russia in 1812. Typhus also killed numerous prisoners in the Nazi concentration camps during World War II.
    
    
    
    • Effects of Colonization. Encounters between European explorers and populations in the rest of the world often introduced local epidemics of extraordinary virulence. Disease killed the entire native (Guanches) population of the Canary Islands in the 16th century. Half the native population of Hispaniola in 1518 was killed by smallpox. Smallpox also ravaged Mexico in the 1520s, killing 150,000 in Tenochtitlán alone, including the emperor, and Peru in the 1530s, aiding the European conquerors. Measles killed a further two million Mexican natives in the 1600s. Some believe that the death of 90 to 95 percent of the Population history of American indigenous peoples of the New World was caused by Old World diseases. As late as 1848–49, as many as 40,000 out of 150,000 Hawaiians are estimated to have died of measles, whooping cough and influenza. The Story Of... Smallpox Smallpox: Eradicating the Scourge
    
    
    There are also a number of unknown diseases that were extremely serious but have now vanished, so the etiology of these diseases cannot be established. The cause of Sweating sickness in 16th-century England, which struck people down in an instant and was more greatly feared even than the bubonic plague, is still unknown.
    
    Concern about possible future pandemics Ebola virus and other quickly lethal diseases Lassa fever, Rift Valley fever, Marburg virus, Ebola and Bolivian hemorrhagic fever are highly contagious and deadly diseases with the theoretical potential to become pandemics. Their ability to spread efficiently enough to cause a pandemic is limited, however, as transmission of these viruses requires close contact with the infected vector. Furthermore, the short time between a vector becoming infectious and the onset of symptoms allows medical professionals to quickly quarantine vectors and prevent them from carrying the pathogen elsewhere. Genetic mutations could occur which could elevate their potential for causing widespread harm, thus close observation by contagious disease specialists is merited.
    
    Antibiotic resistance Antibiotic-resistant "superbugs" may also revive diseases previously regarded as "conquered." Cases of tuberculosis resistant to all traditionally effective treatments have emerged to the great concern of health professionals.
    
    Such common bacteria as Staphylococcus aureus, Serratia marcescens and species of Enterococcus that have developed resistance to the strongest available antibiotics such as vancomycin emerged in the past 20 years as an important cause of hospital-acquired nosocomial infections, and are now colonizing and causing disease in the general population.
    
    In the U.S., 2,000,000 people per year are catching hospital-acquired infections after having been admitted to hospitals to receive medical care for unrelated reasons. The latest number of infections are startling, (2006) equating to 4 new cases per minute. Of those, 90,000+ people die. Organizations like the Center for Disease Control, WHO and Safe Care Campaign are leading the effort to eradicate these avoidable, yet deadly infections.
    
    HIV infection HIV — the virus that causes AIDS — is now considered a global pandemic with infection rates as high as 25% in southern and eastern Africa. Effective education about safer sexual practices and bloodborne infection precautions training have helped to slow down infection rates in several African countries sponsoring national education programs. Infection rates are rising again in Asia and the Americas.
    
    SARS In 2003, there were concerns that Severe acute respiratory syndrome, a new, highly contagious form of atypical pneumonia caused by a coronavirus dubbed SARS-CoV, might become pandemic. Rapid action by national and international health authorities such as the World Health Organization helped slow transmission and eventually broke the chain of transmission, ending the localized epidemics before they could become a pandemic. The disease has not been eradicated, however, and could re-emerge unexpectedly, warranting monitoring and case reporting of suspicious cases of atypical pneumonia.
    
    Avian flu Wild aquatic birds are the natural hosts for a range of influenza A viruses. Occasionally viruses are transmitted from these species to other species and may then cause outbreaks in domestic poultry or (rarely) give rise to a human pandemic.
    
    In February 2004, avian influenza virus was detected in birds in Vietnam, increasing fears of the emergence of new variant strains. It is feared that if the avian influenza virus combines with a human influenza virus (in a bird or a human), the new subtype created could be both highly contagious and highly lethal in humans. Such a subtype could cause a global influenza pandemic, similar to the Spanish Flu, or the lower mortality pandemics such as the Asian Flu and the Hong Kong Flu.
    
    From October 2004 to February 2005, some 3,700 test kits of the 1957 Asian Flu virus were accidentally spread around the world from a lab in the US.
    
    In May 2005, scientists urgently call nations to prepare for a global influenza pandemic that could strike as much as 20% of the world's population.
    
    In October 2005, cases of the avian flu (the deadly strain H5N1) were identified in Turkey. EU Health Commissioner Markos Kyprianou said: "We have received now confirmation that the virus found in Turkey is an avian flu H5N1 virus. There is a direct relationship with viruses found in Russia, Mongolia and China." Cases of bird flu were also identified shortly thereafter in Romania, and then Greece. Possible cases of the virus have also been found in Croatia, Bulgaria and in the United Kingdom.. However, by the end of October only 67 people had died as a result of H5N1 which was atypical of previous influenza pandemics.
    
    Despite sensational media reporting, avian flu cannot yet be categorized as a "pandemic" because the virus cannot yet cause sustained and efficient human-to-human transmission. Cases so far are recognized to have been transmitted from bird to human, but as of December 2006 there have been very few (if any) cases of proven human-to-human transmission. Regular influenza viruses establish infection by attaching to receptors in the throat and lungs, but the avian influenza virus can only attach to receptors located deep in the lungs of humans, requiring close, prolonged contact with infected patients and thus limiting person-to-person transmission. The current WHO phase of pandemic alert is level 3, described as "no or very limited human-to-human transmission."
    
    See also
    • Centers for Disease Control and Prevention (CDC)
    • European Centre for Disease Prevention and Control (ECDC)
    • Endemic (epidemiology)
    • Epidemic
    • List of epidemics
    • Influenza pandemic
    • Pandemic Severity Index
    • Syndemic
    • Medieval demography
    • Infectious disease#Mortality from infectious diseases
    • Biological warfare
    • Disaster#Causes of hypothetical future disasters
    
    
    References
    • Steward's "The Next Global Threat: Pandemic Influenza".
    
    
    Further reading
    • WHO - Authoritative source of information about global health issues
    • Past pandemics that ravaged Europe
    • CDC: Influenza Pandemic Phases
    • U.S. government's pandemic flu and avian flu information site
    
    
    
    
    

    BBC - Horizon - Pandemic
    Details about this Horizon programme, broadcast in 2006 ... Tuesday 7 November 2006, 9pm on BBC Two. A simple virus brewed in the belly of a dead bird is set to embark on a global ...

    Pandemic - Wikipedia, the free encyclopedia
    A pandemic (from Greek παν pan all + δήμος demos people) is an epidemic of infectious disease that spreads through human populations across a large region; for instance a ...

    Pandemic flu Introduction - Health encyclopaedia - NHS Direct
    A severe strain of flu that can spread worldwide ... Flu pandemics are natural events that occur from time to time. Last century, there were flu pandemics in 1918, 1957 and 1968 ...

    Pandemic Studios
    Official site. Company background, past and current projects, press releases and employment opportunities.

    Pandemic Flu
    Global flu surveillance. Content on avian flu, possible impacts of pandemic flu and other resources on the World Health Organisation (WHO) website.

    Pandemic Influenza
    The Government sets out advice on preparing for emergencies and provides a Checklist for business and organisations for pandemic flu planning.

    Pandemic flu : Department of Health - Public health
    A pandemic occurs when a new influenza virus, which people have no immunity to, emerges and starts spreading as easily as normal influenza. The Department of Health is working to ...

    Amazon.co.uk: Pandemic: James Barrington: Books
    Amazon.co.uk: Pandemic: James Barrington: Books ... RRP: £6.99 : Price: £5.49 & eligible for Free UK delivery on orders over £15 with Super Saver Delivery. See details and ...

    Pandemic Flu
    Healthcare worker’s attitudes towards working during pandemic influenza’ is a project designed to explore those factors that might incline/ disincline healthcare workers to ...

    Definition: pandemic from Online Medical Dictionary
    The Online Medical Dictionary is a searchable dictionary of definitions from medicine, science and technology.